{"magazineArticle":{"contentWrapper":{"hideReadArticle":false,"headline":"Don't let shingles interrupt your plans - learn more about your risk","datePublished":"2026-02-23T00:00:00Z","datePublishedFormatted":"February 23 2026","parentHref":{"text":"Behind the Science US edition","href":"/en-us/behind-the-science-us-edition/","openInNewWindowText":null},"nextArticle":{"text":"Next article","href":"/en-us/behind-the-science-us-edition/a-new-horizon-advancing-possibilities-for-severe-asthma/","openInNewWindowText":null},"carouselTitle":"","readTimeMins":3,"captions":{"listenToArticle":"Listen to this article","readTime":"min read time","relatedTags":"Related tags"},"heroImage":{"src":"/media/4kxnp3i1/cassandra-bts-hero-shingles.png?format=webp&v=1dca50efb43ec10","alt":"Cassandra BTS Hero Shingles","darkModeSrc":"/media/4kxnp3i1/cassandra-bts-hero-shingles.png?format=webp&quality=90&v=1dca50efb43ec10"},"author":null,"articleType":null,"videoType":null,"topics":null,"introText":"<p><span class=\"NormalTextRun SCXW97819652 BCX8\">People 50 years and older may think that shingles won’t impact them; however, that may not be the case.</span></p>\n<p>&nbsp;</p>"},"components":[{"type":"rich-text","text":"<div class=\"OutlineElement Ltr SCXW141036020 BCX8\">\n<p class=\"Paragraph SCXW141036020 BCX8\"><span class=\"NormalTextRun SCXW141036020 BCX8\">At 60 years old, Cassandra had a busy, active life, enjoying time with friends and family, especially her three grown children. The last thing she expected was for it to be disrupted by shingles.&nbsp;</span></p>\n<p class=\"Paragraph SCXW141036020 BCX8\"><span class=\"NormalTextRun SCXW141036020 BCX8\">Thinking back, Cassandra remembers happily browsing a garage sale one weekend when she felt something on her back. \"It was a painful bump that felt like a spider bite,\" she recalled,”<span>&nbsp;</span>adding,<span>&nbsp;“</span>I was in a lot of pain.\" After two days,<span>&nbsp;when the pain became unbearable, she contacted her doctor.</span></span>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW141036020 BCX8\">\n<p class=\"Paragraph SCXW141036020 BCX8\"><span class=\"NormalTextRun SCXW141036020 BCX8\">The diagnosis? Cassandra had shingles. </span>&nbsp;</p>\n<div class=\"OutlineElement Ltr SCXW214983075 BCX8\">\n<h2 class=\"Paragraph SCXW214983075 BCX8\"><span class=\"NormalTextRun SCXW214983075 BCX8\">What<span>&nbsp;</span>is<span>&nbsp;shingles?</span></span>&nbsp;</h2>\n</div>\n<div class=\"OutlineElement Ltr SCXW214983075 BCX8\">\n<p class=\"Paragraph SCXW214983075 BCX8\"><span class=\"NormalTextRun SCXW214983075 BCX8\">Shingles<span>&nbsp;(herpes zoster) is&nbsp;</span>a<span>&nbsp;</span>painful, blistering rash, typically occurring on one side of the body, which is<span>&nbsp;</span>caused by the reactivation of the varicella zoster virus (VZV) – the same virus that causes chickenpox.</span><sup><span class=\"NormalTextRun Superscript SCXW214983075 BCX8\" data-fontsize=\"12\">1,2</span>&nbsp;</sup></p>\n</div>\n<div class=\"OutlineElement Ltr SCXW214983075 BCX8\">\n<p class=\"Paragraph SCXW214983075 BCX8\"><span class=\"NormalTextRun CommentStart CommentHighlightPipeRest CommentHighlightRest SCXW214983075 BCX8\">After<span>&nbsp;</span>having<span>&nbsp;chickenpox, the virus stays dormant in&nbsp;</span>the<span>&nbsp;</span>body and can reactivate years later, causing<span>&nbsp;</span>shingles, which can last<span>&nbsp;for weeks</span>.</span><sup><span class=\"NormalTextRun Superscript SCXW214983075 BCX8\" data-fontsize=\"12\">2</span><span class=\"NormalTextRun SCXW214983075 BCX8\"> </span></sup>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW214983075 BCX8\">\n<p class=\"Paragraph SCXW214983075 BCX8\"><span class=\"NormalTextRun SCXW214983075 BCX8\">\"Because of the intense discomfort that can come with<span>&nbsp;</span>the rash, shingles can keep you from doing everyday activities like working and socializing. Having shingles can be an isolating and painful experience,\"<span>&nbsp;explained&nbsp;</span>Dr. Len Friedland, Vice President, Scientific Affairs &amp; Public Health, Vaccines at GSK.&nbsp;</span>&nbsp;</p>\n<div class=\"OutlineElement Ltr SCXW250549395 BCX8\">\n<h2 class=\"Paragraph SCXW250549395 BCX8\"><span class=\"NormalTextRun SCXW250549395 BCX8\">Who may be<span>&nbsp;</span>impacted<span>&nbsp;by shingles?</span></span>&nbsp;</h2>\n</div>\n<div class=\"OutlineElement Ltr SCXW250549395 BCX8\">\n<p class=\"Paragraph SCXW250549395 BCX8\"><span class=\"NormalTextRun SCXW250549395 BCX8\">Adults 50 years and older are at an increased risk for shingles, because the immune system naturally declines with age.</span><sup><span class=\"NormalTextRun Superscript SCXW250549395 BCX8\" data-fontsize=\"12\">3</span></sup><span class=\"NormalTextRun SCXW250549395 BCX8\"><span>&nbsp;In fact, 99% of adults 50 years and older&nbsp;</span>already<span>&nbsp;</span>have the virus that causes shingles inside their body, and it can reactivate at any time, even though<span>&nbsp;</span>not<span>&nbsp;</span>everyone<span>&nbsp;</span>at risk<span>&nbsp;</span>will develop shingles.</span><sup><span class=\"NormalTextRun Superscript CommentStart CommentHighlightPipeRest CommentHighlightRest SCXW250549395 BCX8\" data-fontsize=\"12\">2</span><span class=\"TextRun SCXW250549395 BCX8\" lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun Superscript CommentHighlightPipeRest SCXW250549395 BCX8\" data-fontsize=\"12\">,3</span></span></sup><span class=\"NormalTextRun SCXW250549395 BCX8\"><span>&nbsp;</span>About one million people develop shingles in the US each year.</span><sup><span class=\"NormalTextRun Superscript CommentStart CommentHighlightPipeRest CommentHighlightRest SCXW250549395 BCX8\" data-fontsize=\"12\">2,3</span></sup>&nbsp;</p>\n<div class=\"OutlineElement Ltr SCXW218654017 BCX8\">\n<p class=\"Paragraph SCXW218654017 BCX8\"><span class=\"NormalTextRun CommentStart CommentHighlightPipeClicked CommentHighlightClicked SCXW218654017 BCX8\">While age<span>&nbsp;</span>is the<span>&nbsp;most important risk factor</span>,<span>&nbsp;</span>certain health conditions, like diabetes, chronic kidney disease, and heart disease have been associated with an increased risk of shingles.</span><sup><span class=\"NormalTextRun Superscript SCXW218654017 BCX8\" data-fontsize=\"12\">3,4</span></sup>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW218654017 BCX8\">\n<p class=\"Paragraph SCXW218654017 BCX8\"><span class=\"NormalTextRun SCXW218654017 BCX8\">Cassandra, despite<span>&nbsp;</span>feeling like<span>&nbsp;a well-versed health advocate, was still unaware of how her age increased her risk for shingles.</span><span>&nbsp;</span>“Awareness is the key factor here. So many people that I talked to responded to my experience<span>&nbsp;and</span><span>&nbsp;said that they really&nbsp;</span>weren't<span>&nbsp;aware of the impact that shingles can have,” she added.</span></span>&nbsp;</p>\n<div class=\"OutlineElement Ltr SCXW64569117 BCX8\">\n<h2 class=\"Paragraph SCXW64569117 BCX8\"><span class=\"NormalTextRun SCXW64569117 BCX8\">Are there other potential complications<span>&nbsp;</span>shingles can have?</span>&nbsp;</h2>\n</div>\n<div class=\"OutlineElement Ltr SCXW64569117 BCX8\">\n<p class=\"Paragraph SCXW64569117 BCX8\"><span class=\"NormalTextRun SCXW64569117 BCX8\">While a shingles episode can be a painful and disruptive experience, in some cases, people can develop serious or long-lasting<span>&nbsp;</span></span><span class=\"NormalTextRun SCXW64569117 BCX8\">complications.</span><sup><span class=\"NormalTextRun Superscript SCXW64569117 BCX8\" data-fontsize=\"12\">1,2</span></sup>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW64569117 BCX8\">\n<p class=\"Paragraph SCXW64569117 BCX8\"><span class=\"NormalTextRun SCXW64569117 BCX8\">“People may experience long-lasting pain called post-herpetic neuralgia (PHN)<span>&nbsp;</span>–<span>&nbsp;</span>the most common complication of shingles. Two years later,<span>&nbsp;Cassandra</span><span>&nbsp;still felt the</span><span>&nbsp;pain due to PHN,” Dr.&nbsp;</span>Friedland<span>&nbsp;</span>noted.</span><span class=\"NormalTextRun Superscript SCXW64569117 BCX8\" data-fontsize=\"12\"><sup>1</sup> </span><span class=\"NormalTextRun SCXW64569117 BCX8\">The pain from PHN can be<span>&nbsp;</span>excruciating, persistent, and may<span>&nbsp;</span>impact<span>&nbsp;daily&nbsp;</span>life.<span>&nbsp;</span>PHN occurs in about 10-18% of people who have shingles.</span><sup><span class=\"NormalTextRun Superscript SCXW64569117 BCX8\" data-fontsize=\"12\">1</span></sup><span class=\"NormalTextRun SCXW64569117 BCX8\">&nbsp;</span>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW71412295 BCX8\">\n<h2 class=\"Paragraph SCXW71412295 BCX8\"><span class=\"NormalTextRun SCXW71412295 BCX8\">What can you do to<span>&nbsp;</span>be proactive?  </span>&nbsp;</h2>\n</div>\n<div class=\"OutlineElement Ltr SCXW71412295 BCX8\">\n<p class=\"Paragraph SCXW71412295 BCX8\"><span class=\"NormalTextRun SCXW71412295 BCX8\">Cassandra, who started documenting and sharing her shingles experience since it began, advocates for people 50 and over to talk to their doctor or pharmacist about their risk for shingles<span>&nbsp;</span>and<span>&nbsp;</span>prevention. “I want people to be aware of shingles and feel empowered to speak with their healthcare providers about their risk.”</span>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW71412295 BCX8\">\n<p class=\"Paragraph SCXW71412295 BCX8\"><span class=\"NormalTextRun SCXW71412295 BCX8\">“On a daily basis, I<span>&nbsp;</span>wake up<span>&nbsp;and give ‘thanks’ sincerely for the opportunity to face, challenge, or create something&nbsp;</span>despite<span>&nbsp;my experience with shingles.&nbsp;</span>I’m<span>&nbsp;enjoying life at&nbsp;</span>this<span>&nbsp;</span>age, and I know that<span>&nbsp;</span>there’s<span>&nbsp;so much more out there for me,” Cassandra added.</span></span>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW71412295 BCX8\">\n<p class=\"Paragraph SCXW71412295 BCX8\"><span class=\"NormalTextRun SCXW71412295 BCX8\">\"It’s important to understand your risk for shingles,” said Dr.<span>&nbsp;</span>Friedland. “Talk to your doctor or pharmacist today about your shingles risk<span>&nbsp;</span>and<span>&nbsp;</span>prevention.\"</span>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW71412295 BCX8\">\n<p class=\"Paragraph SCXW71412295 BCX8\"><span class=\"NormalTextRun SCXW71412295 BCX8\">To learn more about your risk for shingles, visit<span>&nbsp;</span><a rel=\"noopener\" href=\"/WhatIsShingles.com\" target=\"_blank\" title=\"Opens in a new window\">WhatIsShingles.com</a>.</span>&nbsp;</p>\n</div>\n<div class=\"OutlineElement Ltr SCXW71412295 BCX8\">\n<p class=\"Paragraph SCXW71412295 BCX8\">&nbsp;</p>\n<p class=\"Paragraph SCXW71412295 BCX8\"><span class=\"NormalTextRun SCXW71412295 BCX8\">Cassandra was compensated by GSK for her participation. This is one person's experience; other people's<span>&nbsp;</span>experiences<span>&nbsp;with shingles may be different.</span></span>&nbsp;</p>\n</div>\n</div>\n</div>\n</div>\n</div>","useGreyBackground":false,"fullWidth":false},{"type":"references","title":"References","references":[{"anchorName":"1.","text":"<p><span class=\"NormalTextRun SCXW27725724 BCX8\">CDC. Shingles Symptoms and Complications. Accessed February 19, 2026. Available at:<span>&nbsp;</span></span><a rel=\"noopener\" href=\"https://www.cdc.gov/shingles/signs-symptoms/\" target=\"_blank\" class=\"Hyperlink SCXW27725724 BCX8\" title=\"Opens in a new window\"><span class=\"NormalTextRun SCXW27725724 BCX8\" data-ccp-charstyle=\"Hyperlink\">https://www.cdc.gov/shingles/signs-symptoms/ </span></a>&nbsp;</p>"},{"anchorName":"2.","text":"<p>CDC About Shingles (Herpes Zoster).<span> </span>Accessed February 19, 2026. Available at: <a rel=\"noopener\" href=\"https://www.cdc.gov/shingles/about/\" target=\"_blank\" title=\"Opens in a new window\">https://www.cdc.gov/shingles/about/ </a></p>"},{"anchorName":"3.","text":"<p><span class=\"NormalTextRun SCXW144252996 BCX8\">CDC. Clinical Overview of Shingles (Herpes Zoster). Accessed February 19, 2026. Available at:<span>&nbsp;</span></span><a rel=\"noreferrer noopener\" href=\"https://www.cdc.gov/shingles/hcp/clinical-overview/\" target=\"_blank\" class=\"Hyperlink SCXW144252996 BCX8\" title=\"Opens in a new window\"><span class=\"NormalTextRun SCXW144252996 BCX8\">https://www.cdc.gov/shingles/hcp/clinical-overview/</span></a><span class=\"NormalTextRun SCXW144252996 BCX8\">&nbsp;&nbsp;</span>&nbsp;</p>"},{"anchorName":"","text":"<p><span class=\"NormalTextRun SCXW99303368 BCX8\">Marra F, Parhar K, Huang B, Vadlamudi N. Risk Factors for Herpes Zoster Infection: A Meta-Analysis. Open Forum Infectious Diseases. 2020;7(1):ofaa005. Available at:<span>&nbsp;</span></span><a rel=\"noreferrer noopener\" href=\"https://doi.org/10.1093/ofid/ofaa005\" target=\"_blank\" class=\"Hyperlink SCXW99303368 BCX8\" title=\"Opens in a new window\"><span class=\"NormalTextRun SCXW99303368 BCX8\">https://doi.org/10.1093/ofid/ofaa005</span></a>&nbsp;</p>"}]},{"type":"varied-signpost-grid","title":"You might also like","layoutPattern":4,"pages":[{"title":"Company","content":"We unite science, technology and talent to get ahead of disease together","image":{"src":"/media/suilv4ve/dna-and-tech-science-image-rgb.jpg?width=427&height=533&format=webp&quality=100&v=1dcb546428b35f0","alt":"DNA And Tech Science Image","darkModeSrc":"/media/suilv4ve/dna-and-tech-science-image-rgb.jpg?width=427&height=533&format=webp&quality=90&v=1dcb546428b35f0"},"link":{"text":"Company","href":"/en-us/company/","openInNewWindowText":null}},{"title":"Vaccines","content":"Protecting people from serious disease for well over 100 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