In response to the European regulatory review of paroxetine (the "Article 31 referral" process), GSK conducted an analysis of suicidality in patients receiving paroxetine and other antidepressants, based on data from the UK General Practice Research Database (GPRD). The GPRD is a computerized database of anonymous medical records from primary care physicians in the UK that is publicly available for research purposes and is managed by the Medicines & Healthcare products Regulatory Agency (MHRA) in London.
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